Disposable Roller Bottle with Vent Cap
Description
Technical Parameters
The Disposable Roller Bottle with Vent Cap engineered by OptiMedvo is a premium single-use vessel designed for large-scale industrial cell culture, biological manufacturing, and vaccine production workflows.
As a specialized commercial supplier, OptiMedvo utilizes medical-grade, high-clarity polystyrene (PS) that strictly adheres to USP Class VI requirements, ensuring an optimal growth environment with excellent structural integrity.
Each disposable roller bottle with vent cap features a precision-molded 0.22µm hydrophobic membrane within the cap, facilitating uninterrupted, sterile gas exchange while eliminating the risk of cross-contamination during active scaling phases.
Purpose-built for automation and automated bottle-rolling systems, this durable disposable roller bottle with vent cap minimizes downstream risks and maximizes viable cell surface density across demanding bioprocess applications.
Key Product Advantages & Features
The cap is integrated with a high-permeability, hydrophobic 0.22µm PTFE membrane. This allows continuous equilibration of oxygen and carbon dioxide while acting as an absolute barrier against microbial contaminants, ensuring stable pH levels inside the vessel without manual venting or risk of fluid loss.
01
Advanced vacuum-gas plasma treatment modifies the hydrophobic polystyrene matrix into a highly hydrophilic, negatively charged growth surface. This uniform surface chemistry guarantees rapid, consistent cell attachment, uniform monolayer distribution, and significantly elevated cell proliferation yields.
02
Manufactured utilizing a proprietary single-piece blow-molding process. By removing traditional horizontal seams, the structural design completely eliminates weak points susceptible to pressure cracks, leaks, or optical distortions under prolonged automated rotational torque.
03
Equipped with deep, high-torque vertical ridges along the outer collar and an anti-slip base profile. This mechanical architecture delivers exceptional traction on standard commercial roller racks, mitigating rotational slippage and ensuring smooth, synchronized automated indexing.
04
Specifications
|
Specification |
1000 mL 2000 mL 3000mL 5000 mL |
|
Cap Type |
Plug Seal Vent |
|
Surface |
Non-treated TC-treated |
|
Materials |
Bottle Body:Polystyrene (PS), Bottle |
|
Cap |
High-density Polyethylene (HDPE), Cap |
|
Filter Membrane |
Polytetrafluoroethylene (PTFE), conforming to USP Class VI standards |
|
Volume |
Appro.Cell Growth |
Working |
Cap Style |
Height |
B.D* |
B.N.D* |
Sterile |
Qty.Per |
Qty.Per |
|
2000 |
1900 |
300-400 |
Plug seal |
273.5 |
116.5 |
44.9 |
Y |
1 |
12 |
|
2000 |
1900 |
300-400 |
Vent |
273.5 |
116.5 |
44.9 |
Y |
1 |
12 |
|
2000 |
1900 |
300-400 |
Easy grip plug seal |
273.5 |
116.5 |
44.9 |
Y |
1 |
12 |
|
2000 |
1900 |
300-400 |
Easy grip vent |
273.5 |
116.5 |
44.9 |
Y |
1 |
12 |
|
5000 |
4250 |
850-1300 |
Plug seal |
500.0 |
121.5 |
44.9 |
Y |
1 |
12 |
|
5000 |
4250 |
850-1300 |
Vent |
500.0 |
121.5 |
44.9 |
Y |
1 |
12 |
Application Scenarios
Industrial Viral & Bacterial Vaccine Manufacturing
Monoclonal Antibody (mAb) & Recombinant Protein Synthesis
Commercial Contract Research and Scale-Up
Why Select OptiMedvo As Your Supply Partner
- All manufacturing phases are conducted continuously within our state-of-the-art, fully automated 100,000-grade (ISO Class 7) cleanroom facilities. This environment mitigates ambient particulate matter and completely eliminates manual human contact with raw surfaces during molding.
- Every delivery batch undergoes mandatory, comprehensive lot-traceability procedures. We issue a comprehensive Certificate of Analysis (CoA) with each shipment, documenting validated endotoxin benchmarks (<0.1 EU/mL) and verified non-cytotoxicity profiles.
- Backed by a high-capacity warehouse layout, we provide direct container shipping, localized customs documentation assistance, and customizable outer packaging layouts designed specifically to survive extreme international freight transits without loss of sterile envelope integrity.
Our Certificate
fAQ
Q1: How does your bulk cell culture roller bottle ensure stable pH balancing during long-term scaling processes?
A: Our cell culture roller bottle incorporates an advanced hydrophobic vent cap containing a 0.22µm PTFE membrane filter. This architecture facilitates passive, continuous gas equilibration between the vessel headspace and the external incubator environment, maintaining precise, stable pH without needing manual cap-loosening steps.
Q2: Can your disposable roller bottle with vent cap be utilized interchangeably across different automated rolling machinery?
A: Yes. OptiMedvo designs these bottles to standard international laboratory and industrial specifications. The outer dimension and tracking ring profile match industry standards perfectly, preventing slippage or misalignment on major global automated rolling rack systems.
Q3: What treatment methodology does the factory apply to guarantee uniform cell attachment?
A: As an experienced B2B manufacturer, we utilize vacuum-gas plasma surface treatment across our entire automated production lines. This process modifies the interior polystyrene surface evenly, ensuring a consistent hydrophilic density that promotes uniform cell distribution and minimizes localized clustering.
Q4: Are your vented roller bottles certified free from biological contamination?
A: Absolutely. All items are sterilized via validated gamma irradiation protocols according to ISO 11137 regulations, reaching a Sterility Assurance Level (SAL) of 10⁻⁶. Furthermore, every batch is certified DNase-free, RNase-free, and non-pyrogenic with an endotoxin limit under 0.1 EU/mL.
Q5: What are the primary lead times and options available for wholesale medical consumables from your factory?
A: Standard stock shipments leave our facility within 7–15 business days. For customized OEM adjustments, large-scale wholesale medical consumables orders, or private-label packaging requirements, our logistics team establishes a tailored delivery framework based on your localized seaport requirements.
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